Kao CJ*, Charmsaz S*, Alden SL, Brancati M, Li HL, Balaji A, Munjal K, Howe K, Mitchell S, Leatherman J, Griffin E, Nakazawa M, Tsai HL, Danilova L, Thoburn C, Gizzi J, Gross NE, Hernandez A, Coyne EM, Shin SM, Babu JS, Apostol GW, Durham J, Christmas BJ, Konig MF, Lipson EJ, Naidoo J, Cappelli LC, Pabani A, Ged Y, Baretti M, Brahmer J, Hoffman-Censits J, Seiwert TY, Garonce-Hediger R, Guha A, Bansal S, Tang L, Jaffee EM, Chandler GS, Mohindra R, Ho WJ#, Yarchoan M#.
*co-first; #co-corresponding
J Clin Invest. 2024 Aug 29; 134(20): e176567.
Media coverage: Hopkins Newswise
Immune-related events in individuals with solid tumors on immunotherapy associate with Th17 and Th2 signatures
Grasset EM#, Deshpande A, Lee JW, Cho Y, Shin SM, Coyne EM, Hernandez A, Yuan X, Zhang Z, Cimino-Mathews A, Ewald AJ, Ho WJ#.
#co-corresponding
Oncogene. 2024 Sep;43(39):2927-2937
Media coverage: AAAS EurekAlert! the Johns Hopkins NewsLetter Hopkins Newswise
Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells
Gross NE*, Zhang Z*, Mitchell JT, Charmsaz S, Hernandez AG, Coyne EM, Shin SM, Vargas Carvajal DC, Sidiropoulos DN, Cho Y, Mo G, Yuan X, Cannon C, Suresh Babu J, Lyman MR, Armstrong T, Kagohara LT, Bever KM, Le DT, Jaffee EM, Fertig EJ, Ho WJ.
*co-first
Phosphodiesterase-5 inhibition collaborates with vaccine-based immunotherapy to reprogram myeloid cells in pancreatic ductal adenocarcinoma
Shin SM, Hernandez A, Coyne E, Munjal K, Gross NE, Charmsaz S, Yuan X, Yang H, Ho WJ.
CyTOF protocol for immune monitoring of solid tumors from mouse models
Sidiropoulos DN, Stein-O'Brien GL, Danilova L, Gross NE, Charmsaz S, Xavier S, Leatherman J, Wang H, Yarchoan M, Jaffee EM, Fertig EJ, Ho WJ.
Integrated T cell cytometry metrics for immune-monitoring applications in immunotherapy clinical trials
Zabransky DJ, Danilova L, Leatherman JM, Lopez-Vidal TY, Sanchez J, Charmsaz S, Gross NE, Shin S, Yuan X, Hernandez A, Yang H, Xavier S, Shu D, Saeed A, Munjal K, Kamdar Z, Kagohara LT, Jaffee EM, Yarchoan M#, Ho WJ#.
#co-corresponding
Profiling of syngeneic mouse HCC tumor models as a framework to understand anti-PD-1 sensitive tumor microenvironments
Ho WJ*, Zhu Q*, Durham J, Popovic A, Xavier S, Leatherman J, Mohan A, Mo G, Zhang S, Gross N, Charmsaz S, Lin D, Quong D, Wilt B, Kamel IR, Weiss M, Philosophe B, Burkhart R, Burns WR, Shubert C, Ejaz A, He J, Deshpande A, Danilova L, Stein-O'Brien G, Sugar EA, Laheru DA, Anders RA, Fertig EJ, Jaffee EM, Yarchoan M.
*co-first
Nat Cancer. 2021 Sep;2(9):891-903.
Selected for cover art (by Soren, Nicole, Won)
Media coverage: AAAS EurekAlert! Hopkins Newswise, OncLive, ASCO Post
Neoadjuvant cabozantinib and nivolumab converts locally advanced HCC into resectable disease with enhanced antitumor immunity
Ho WJ*, Croessmann S*, Lin J*, Phyo ZH, Charmsaz S, Danilova L, Mohan AA, Gross NE, Chen F, Dong J, Aggarwal D, Bai Y, Wang J, He J, Leatherman JM, Yarchoan M, Armstrong TD, Zaidi N, Fertig EJ, Denny JC, Park BH#, Zhang ZY#, Jaffee EM#.
*co-first; #co-corresponding
Systemic inhibition of PTPN22 augments anticancer immunity
Ho WJ, Erbe R, Danilova L, Phyo Z, Bigelow E, Stein-O'Brien G, Thomas DL 2nd, Charmsaz S, Gross N, Woolman S, Cruz K, Munday RM, Zaidi N, Armstrong TD, Sztein MB, Yarchoan M, Thompson ED, Jaffee EM#, Fertig EJ#.
#co-corresponding
Genome Biol. 2021 May 13;22(1):154.
Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways
A global live cell barcoding approach for multiplexed mass cytometry profiling of mouse tumors
Ho WJ, Yarchoan M, Charmsaz S, Munday RM, Danilova L, Sztein MB, Fertig EJ, Jaffee EM.
JCI Insight. 2020 Jan 30;5(2):e132286.
